| update on bird flu from NAS | <– Date –> <– Thread –> |
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From: William Weir (wweir1 |
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| Date: Tue, 29 Jul 2008 11:10:27 -0700 (PDT) | |
The Proceedings of the National Academy of Sciences (PNAS) at http://www.pnas.org/content/105/21/7558.full recently included this update on avian influenze (a/k/a bird flu): Avian influenza viruses within the H5 and H7 subtype continue to pose a major public health threat. Since 2004, highly pathogenic avian influenza (HPAI) H5N1 viruses have resulted in >380 cases of laboratory-confirmed human infection in 14 countries (1<http://www.pnas.org/content/105/21/7558.full#ref-1>). Despite the high virulence of H5N1 viruses observed in humans and mammalian models (2 <http://www.pnas.org/content/105/21/7558.full#ref-2>), human-to-human transmission has been only rarely documented. Which I put together with other data and information to mean, 1> bird flu is still smoldering in 14 other lands (especially Egypt and Indonesia, according to WHO reports) 2> it is highly virulent (killing over half those who get it), 3> human-to-human transmission has been documented (though rarely) 4> when the virus (probably H5N1, maybe H7N7) re-assorts with a seasonal flu virus (already with efficient transmissability human to human) in a host (e.g. a pig or human), unless the public health system (underfunded) contains it (very difficult but may be possible as it happens again and again), a pandemic (global human epidemic) is likely.
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