| Health-care | <– Date –> <– Thread –> |
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From: Robert Tapp (tappx001 |
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| Date: Mon, 7 Sep 2009 16:46:43 -0700 (PDT) | |
[A colleague of Hadler's at UNC Medical School urged me to get this
book. Many parallels to Becca's concern]
(this is lengthy because of the urgency of the US situation)Clearly we spend more and get less than any other developed country. And the <health> share of the GDP is growing, and is already a major cause of bankruptcy and foreclosure. Equally clearly, the monies being spent by defenders of this status quo weigh heavily on congressional prudence!
I've just finished a rare book by Nortin Hadler. Rare because he is a physician, researcher, educator who has voiced his dissatisfactions loudly. Below are my recordings from the book (and no substitute for full reading!).. If you have little time, skip to the final section, beginning at Indemnifying Rational, Not Rationed, Health Care.
Bob -------------------Hadler, Nortin M. 2008. Worried sick : a prescription for health in an overtreated America. Chapel Hill: University of North Carolina Press.
Acknowledgment xi Introduction 1 one The Methuselah Complex 9 two The Heart of the Matter 15 three Risky Business: Cholesterol, Blood Sugar, and Blood Pressure 33 4 You Are Not What You Eat 57 5 Gut Check 65 6 Breast Cancer Prevention: Screening the Evidence 77 seven The Beleaguered Prostate 95 8 Disease Mongering 105 9 Creakiness 111 ten It's in Your Mind 135 11 Aging Is Not a Disease 153 12 Working to Death 171 13 "Alternative" Therapies Are Not "Complementary" 191 14 Assuring Health, Insuring Disease 213The wealth of health information disseminated by all sorts of health- care vendors, including those in the medical profession, may be intended as helpful but often is not. Much of this information does violence to our sense of invincibility without doing equivalent good for our health or longevity. This book levels the playing field. ...is imbued with the teachings of Karl Popper..... Truth, he taught, is only the hypothesis that is yet to be disproved. 3 Medicalization is the process by which the morbidity is framed by the person as a medical illness for which medical treatment could or should be sought. 4 I am not setting out to turn you into biostatisticians and epidemiologists. I am setting out to mold your critical skills so that you can recognize and contend with the unfounded assertions, tortured and massaged data, and egregious marketing that has always been present but is now industrialized. There is no other way to avoid sacrificing the sense that you are //well to medicalization, or worse yet, losing your actual wellness to iatrogenicity, the illnesses that are caused by medical treatments. And there is no other way to recruit you to my "hidden" agenda: fomenting a debate that demystifies "modern" medicine so that we can promulgate a rational health-care delivery system and underwrite its cost. 6f A millennium ago, Europe sacrificed its intellectual roots and traditions to . superstition and wallowed in the Dark Ages. Meanwhile, science, philosophy and medicine thrived in the Arab world, with centers of excellence such a: Alexandria. Japanese and Chinese medicine and medical education also advanced in rationality and organization. 196 Ginseng and echinacea are useful only as statements that you have disposable income and are unfazed by the clinical trials that fail to discern benefit for either, in particular for ginseng for dementia and echinacea for the common cold. ...As far as I'm concerned, they are all worthless unless they taste good. 204
. The Retired WorkerI am saddling you, the reader, with quite a burden in terms of your health. Even if my profession approached perfection in the healing art, it would not be enough without your essential contributions. Youmust be aware of much more
than your own socioeconomic status. You must be aware of much more thanyour own sense of accomplishment at home and at work. The greatest burden I am placing on you is the understanding of the political context that shapes your well-being. If yours is lacking, you will pay a personal price. If too many around you are lacking in this understanding, you will find yourself in a world
that is angry, even desperate and possibly violent.As for the octogenarians, to be well at your age means you have managed to cope with a laundry list of life challenges. To be well, now, means you voyaged through life in a comforting socioeconomic stratum. To be well, now, means you managed to avoid being mired in circumstances that rendered you disaffected
or hostile at work or at home. To be well means you were sophisticatedenough, or lucky enough in your choice of providers, to have negotiated with health-care professionals so as to enjoy interactions with favorable benefit/risk ratios, to avoid iatrogenesis, and to avoid medicalization. I have written this book to offer guideposts to the generations behind you who aspire to be well octogenarians. However, if you're a well octogenarian, then what? You are of a
ripe old age. Can this be an enjoyable and joyful time of life?Family and community are the precious underpinnings for a joyful last decade. The other prerequisite relates to the entitlement of senior citizens to the best health care money can buy. Senior citizens are a powerful lobby in that
regard. However, they have been duped into marching arm-in-arm with thepharmaceutical industry, the hospital industry, and components of the medical industry. Is Plan D of Medica re an advance in health care or in Type II Medical Malpractice? Analysis of Medicare data documents that excess spending and excessivecare transfers considerable wealth but does nothing for the well-being or satisfaction of the elderly. All they gain is the hazards of iatrogenicity. Beware of medical schemes that are offered to prolong your life. For octogenarians,
the goals of self-effectualness, independence, interaction, and comfortare primary. Besides, the goal of prolongation of Iife by medical interventions
WORKING TO DEATH I 18gfor anything but acute intercurrent events is even more ephemeral at eighty
than it was at sixty.Beware of the use of pharmaceuticals to serve the primary goals of selfeffectualness,
independence, interaction, and comfort. The drugs that are availableto serve these goals are limited in number and efficacy. They are severely limited in effectiveness. Their therapeutic indices, the tightness of their benefit/ risk ratios, are inversely related to your age. That means that side effects are almost as likely as benefits. Don't take any drug for these goals that is not clearly moving you in the right direction. Negotiate with your doctor for trials of agents where the trial has an a priori end point: either you are clearly better or you will stop the drug. Otherwise, you will join the majority of your cohort that is consuming pills; 40 percent consumes five or more different prescription drugs each week, and one out of every eight pill takers suffers a serious side
effect each year.The same sophistication in health-care utilization that will avail those in the generations that follow is as relevant to you who are attempting to enjoy the ripe old age you have attained. I wish you love. I wish you friendship. I wish you
well. 190 I WORKING TO DEATHals of acupuncture, physical therapy, and massage. There are even randomized controlled trials of "therapeutic touch" and "distant healing" that yield little
encouragement, if any.The one exception relates to spinal manipulation. In 1987 my colleagues and I published a randomized controlled trial we had performed with funding from
the Robert Wood Johnson Foundation. We recruited from the communityyoung people who were suffering from acute regional back pain for less than a month, who had never undergone any form of spinal manipulation in the past, and whose predicament was not confounded by issues of work incapacity. All were examined by me and reassured. All underwent a mobilization: they were gently moved from side to side and administered flexion/extension by my colleague
and coinvestigator, a professor of family medicine who had been trainedby James Cyriax in London in "orthopedic medicine." Half underwent a longlever arm, high velocity, lateral thrust "back crack" - the bread-and-butter maneuver of osteopathy. All subjects felt better on leaving the office, regardless of the modality. For those who were hurting for two weeks or less at the time of the intervention, all were better two weeks later, and the pace of healing was not influenced by the modality. For those who were hurting for two to four weeks at the time of the intervention, all were better two weeks later, but those who
received the single "back crack" healed more rapidly.The world of spinal manipulation holds this investigation up as a landmark.
It has been reproduced many times. However, it does not reproduce in anyother subset of the universe of people suffering back pain. Only those who have
nonconfounded regional backache for two to four weeks are advantaged byspinal manipulation, and only by a single encounter. Furthermore, the benefit
is measured in days of extra relief, not more.All these studies are an attempt to test the therapeutic modality independent of the treatment act. If the treatment act is allowed to play out, benefit is demonstrated
more often than not. The risk of most of these modalities is low. Thereare anecdotal reports of neurological consequences of manipulating the neck.
Otherwise, untoward physical consequences are rare. The Ethical ConundrumI am willing to admit that much that is therapeutic in the practice of medicine as purveyed by my guild relates to the treatment act and not just to the modality. I am further willing to admit that many of our therapeutic modalities barely
210 I "ALTERNATIVE" THERAPIES ARE NOT "COMPLEMENTARY"pass scientific muster. Furthermore, I am willing to admit that becoming a medical patient is entering the medical therapeutic envelope more often than not, and clearly too often. This book stands witness to the fact that I am willing to recognize and decry many a medical modality that masquerades as "proven effective." It takes its place in the scientific tradition that Western medicine holds sacrosanct and that is embodied in the philosophy of Karl Popper. The proud history of Western medicine is the history of recognizing, decrying, and discarding all therapeutic modalities found to be lacking in adequate benefit/ risk ratios (though not always with blinding alacrity). The process may be inefficient, is sometimes contentious, and currently is denigrated. But it is sacrosanct.
Therein lies progress.Alternative and complementary modalities are widely perceived to work and indeed have a life of their own. They survive in the face of science by relying on such lame defense as the idiosyncrasies of their application or preparation; practitioners argue that they do something differently or purvey something different than whatever proved ineffective in a randomized controlled trial. Circumlocution masquerades as progress. The treatment act, palliative or not, is grounded in such fallacious reasoning, in beliefs that are buffered from refutation.
There is no progress, only the self-perpetuation of the treatment acts."So what?" you ask. "Who cares if the modalities are fatuous, as long as the
treatment act is not harmful and the clinical effect is palliative?"I do. I care if fellow citizens are being duped into thinking that they are participating in a therapeutic contract that is more than magical. I care that I am being forced to underwrite such magical therapies. And I care if people are
unknowingly being drawn into a therapeutic envelope. Life has many aspects that are beyond reason. Poets conceptualize "love"better than neurobiologists dissect it. Religion has a place, for some a healing place. There are even attempts to study the fashion in which religion might create a therapeutic envelope. Ethnic identities, cultural norms, and social constructions
all have their place in the fabric of our lives. We need our beliefs asindividuals, and we need their pluralism as a global village. All can provide for beauty, caring, and comfort. All can have excesses and require close scrutiny in this regard. None of these aspects oflife is supported by health insurance. Individuals
choose to participate in and support these :valuesin their own fashion.They are not aspects oflife supported by health insurance. Treatment acts based on modalities whose effectiveness has been scientifically refuted are not treatment acts; they are belief systems. I am aware of no insurance scheme that sets
"ALTERNATIVE" THERAPIES ARE NOT "COMPLEMENTARY" I 211"quality" is not the goal, it is the process. Efficacy first, then quality promotes
effectiveness. There is an "Effectiveness Movement," bloodied and bent but unbowed. Itcan muster far more illustrative science than the Quality Movement. Worried Sick is exemplar. But the forces that thwart the demand for effectiveness are powerful, wealthy, and predictable. Most of the high-ticket items (procedures and pharmaceuticals) are minimally effective or ineffective. Many of these are considered standards of care. Many are cash cows, touted by vested interests. They may be resistant to a voice such as mine, but I can teach you how to advocate
for yourself.Let's say I have to treat more than fifty people in the hope of doing something important for one. Do you believe that's an effective treatment? Nearly all of us involved in biostatistics will tell you that such an outcome is barely measurable and not likely to reproduce. Here's a partial list of treatments (most the topic of chapters herein) that would not even qualify at this level of effectiveness based
on scientific trials designed to test their efficacy:• Coronary artery bypass grafts, angioplasties, or stents to save lives or
improve symptoms • Arthroscopy for knee pain • Any surgery for backache • Statin therapy to reduce cholesterol and thereby save lives • Newer antidepressants for situational depression • Drugs for decreased bone density • PSA screening and radical prostatectomy to save lives • Screening mammography to save lives • Many a cancer treatment to save livesThe list of treatments that have been studied and fail at the one-in- fifty levelgoes on and on, including many of the new drugs touted as "breakthroughs." Many surgical treatments have yet to be studied. From my perspective as a clinician who has cared for patients and taught students for over three decades, ifI have to treat more than twenty patients to do something really meaningful for one, I regard the treatment as marginal; I do not prescribe or advocate it and would have no problem if it was not covered by health insurance. Furthermore, designing trials to test whether new or old treatments meet this one-in-twenty level of effectivenessis not difficult, expensive, or time-consuming. We would no longer be marketed to prescribe and consume minimally effective treatments or treatments
that offered no important improvement over the tried and true. ASSURING HEALTH, INSURING DISEASE I 21gIfwe have effectiveness at the base of our health-care insurance system, adding
cost-effectiveness and quality would be rational and straightforward. Wecould well afford such a rational health-care delivery system, with most of the
$2 trillion to spare. We would be more "high performance" than any othercountry. And our unsung, well-trained, and caring physicians, nurses, and allied health professionals could get back to serving patients instead of the healthcare
delivery system. Indemnifying Rational, Not Rationed, Health CareAt the outset of Worried Sick, I promised to set forth a "solution" that would promulgate rational health care. I also acknowledged that no such solution was possible until the people, both the well and the ill, were prepared to seek and recognize the sophisms that riddle America's vaunted "health-care delivery system." If I've done my job and you've done your reading, you are prepared, indeed. I will keep my promise. You are also prepared to grasp the substance of
the solution I am proposing.The current approach to health benefits in the United States is uneven, unwieldy,
ineffective, and unsustainable. Nearly all attempts at reform target itscostliness with the assumption that improvement will translate into an improved benefit/cost ratio. The shibboleth of the current iteration is "quality," a construct weighted heavily toward efficiency (usually in the industrial sense of "throughput"). It is argued that if care was delivered more efficiently, it would be less costly and therefore more cost -effective. This iteration of reform, I predict,
will prove as counterproductive as the precedents of recent decades.Worried Sick is a primer on the fashion in which science calls into question the basic tenet of the "quality improvement" approach. If medicalization and Type II Medical Malpractice are the scourge, then the solution is to first target effectiveness to improve the benefit/cost ratio. Yes, "evidence-based medicine" (EBM) provides the scientific footing, but no more. But the innovation is to harness evidence to the task of informing effectiveness. If any clinical interaction has been studied and cannot be shown to be meaningfully effective, it is worthless
at any cost.Such a simple precept demands definition of "meaningfully effective" in a fashion that vests all interests in the well-being of the recipient of the care and caring. The definition must preclude any other motivation. There are very few unequivocally salutary events in medicine or in life. Hence, I am proposing an indemnity plan that institutionalizes this creed. It is conceived as a benefits plan
220 I ASSURING HEALTH, INSURING DISEASEto be provided by larger employers, although it is expected that mechanisms will be developed to offer the plan to smaller employers (through chamber of commerce organizations, for example). In fact, this approach could be state based; each state would fund a plan based on income-tax revenues with provision
for those who have no substantial gainful employment. But the modeling we have done, for convenience, is for an employer-based plan. Financing of the PlanEmployers will contribute a fixed sum - 12 percent of wages. It matters little if these moneys are collected by the state as a form of income tax on all employees (my preference) or contributed by all employers and wage earners individually. The money generated needs to be used to purchase the form of private insurance I will describe. I fear that a federal program will be no match for the pressures
of Big Pharma and similar political action committees, a fear that trulysaddens me. However, competing private-sector insurance companies constituted as I will describe should live out the "free-market dream," or all is lost.
These moneys will be apportioned as follows:1. Administrative costs for running the indemnity scheme will be fixed at
1percent of wages. 2. Likewise, 1 percent will be the "profit."3. There will be multiple codicils attached to the contracts of employees of
the indemnity scheme regarding conflicts of interest. Furthermore, no officer will be allowed remuneration greater than five times that of the average wage of those employed by the plan.That leaves some 10 percent of annual wages, tithed monthly, available for Plans
A and B of the indemnity scheme. Plan A: The Health PlanAs you are aware (since I emphasize it repeatedly in Worried Sick), there are important
lessons that derive from the work of social epidemiologists. Life-courseepidemiology pegs our optimal species longevity near eighty-five. The major confounders to longevity reside in the course of life in a resource- advantaged
country such as the United States. When one examines our mortal hazard, some 75 percent of the risk is subsumed by two questions: ASSURINC:; HEALTH, INSURINC:; DISEASE I 221 1. Are you comfortable in your socioeconomic status? 2. Are you satisfied in your employment?Based on these realities, monies in Plan A will be available to the worker to underwrite self-improvement activities of her or his choice, which are offered by professionals licensed in the state of residence. Examples include English as a second language, skills training, child care, and clinical activities not covered in Plan B, such as the services of licensed complementary and alternative health-care providers. The indemnity scheme will offer an advisory service, informing the worker of the likelihood that particular services will diminish
their mortal hazard as discussed above.Plan A is financed with the moneys not expended in Plan B. Plan A is not a shared-risk pool. Co-pay will be a function of years of service and cost to the plan. Indemnified workers will be educated to realize that moneys poorly spent
in Plan B compromise their Plan A resources. Likewise, moneys not poorlyspent in Plan B provide more of the advantages inherent in Plan A. Moneys in the employee's Plan A account that are not expended transform into a pension at retirement or are expended to support Plan Bpremiums when the employee is between jobs. These moneys are conservatively invested and secured from
any other expenditure. Plan B: The Disease PlanPlan B is the more traditional "health-insurance" component of the indemnity
scheme. It follows from the theoretical considerations underlying Plan Athat only some 25 percent of our mortal hazard can be ascribed to "proximatecause
epidemiology," or the diagnoses on our death certificates. Underwriting programs designed to improve longevity are limited by this reality. PlanB underwrites this "disease insurance" by indemnifying those interventions that are designed to manage or cure intercurrent disease so that one is afforded the longevity predicted by life-course epidemiology. "Disease insurance" also indemnifies interventions that palliate illnesses consequent to diseases that
cannot be cured.Plan B will be informed by a vast science, the work product of international collaborations of investigators who are quantifying the evidentiary basis of diagnostic
and therapeutic options. Several thousand such documents are in thepublic domain, supplemented by FDA analyses and, to a lesser extent, by similar analyses in journals. It is estimated that some 10,000 systematic reviews will
222 I ASSURING HEALTH, INSURING DISEASEbe needed for a comprehensive EBM library. Furthermore, it is estimated that reviews must be updated with some frequency, approaching every four years. This effort will not be duplicated in the indemnity scheme. Rather, a group of individuals trained in this effort will cull the practical essence of the extant EBM
library.Realize that the thrust of the EBM movement is whether there is reliable evidence for or against a particular clinical interface. That question is only the first order for" disease insurance." The reviewing group in the indemnity scheme will be charged to review the EBM literature with the goal of discerning effectiveness.
If reasoned attempts have failed to discern benefit from a particularintervention, that intervention will be considered useless and therefore not indemnified
under Plan B.Plan B only indemn ifies fully when there is evidence that the clinical interface
leads to a meaningful outcome for the individual patient:1. For a "hard outcome" (death, stroke, heart attack, renal failure, etc.),
interventions are indemnified if they clearly advantage one in every twenty patients treated (NNT = 20).2. For a "soft outcome" (feel better, function better, etc.), there must be a
clear advantage to one in every five patients treated (NNT = 5).These cutoffs are set at my level of comfort. They are driven by one's philosophy of life, one's value system. I would argue that a NNT = 50 is ephemeral; it is too small a health effect to measure reliably. I would countenance a debate as to setting the cutoff at greater than NNT = 20 but less than NNT = 50 for hard outcomes. However, the debate must be transparent and public, so that all who are indemnified understand that this indemnity plan is not deSigned to "save money." Rather it is deSigned to "saveyour money," since moneys not expended in Plan B revert to Plan A. All of us have to realize that by setting the cutoff
at NNT = 20, we are demanding something approaching a 5 percent absolutelikelihood of "hard" benefit. If the plan were to share the cost of interventions with lesser likelihood of benefit, all the indemnified are tithed and each of the
indemnified have less Plan A largesse as a consequence. However, the debate is to NNT cutoff, not co-pay.To the extent that any clinical interface (diagnostic or therapeutic) falls short of NNT criteria, co-pay will be levied. Furthermore, co-pay is categorical- either 100 percent or nothing. The plan will utilize the federal Medicare- billing scheme with the above co-pay provisions. Many chapters in Worried Sick bear witness that nearly all the elective "high-ticket" items (in terms of expense per event
ASSURING HEALTH, INSURING DISEASE I 223or cumulative expense for screening/prevention) will not be covered in Plan B without 100 percent co-pay according to the criteria I am advocating. For example, the co-pay for coronary angioplasty, stenting, and bypass grafting would be 100 percent. If you are convinced you need it, you can use your Plan
A moneys, and when they run out, you can payout of pocket. This is not a"hard-nosed" posture to rationing; Plan B will not pay because the data says
these procedures are not worth paying for.Furthermore, there is data speaking to the effectiveness of all pharmaceuticals
licensed by the FDA for thirty years. If an agent does not meet Plan B'seffectiveness criteria when compared to an older agent, there will be 100 percent co-pay. Therefore, the co-pay for cholesterol screening as primary prevention would be 100 percent, as would the cost of pharmaceutically altering serum
cholesterol levels as primary prevention.Obviously, this approach will seem counterintuitive in the United States, a country that is medicalized both in terms of personal health and social constructions
regarding medical miracles. The introduction of the indemnityscheme will call for a major public education and public-relations effort. The readership of Worried Sick will be recruited to this effort. It is greatly facilitated by the realization that all moneys not expended in Plan B reverts to Plan A. Therefore, the levying of co-payments is designed to spare the insured unnecessary/
ineffective medicine and not to "save" money. The patient has the rightto draw available funds from her/his Plan A reserve to cover co-pay. However, the insured will be asked to sign a form acknowledging an understanding that the plan is levying co-pay because the value of the particular intervention has
proved elusive in systematic studies, and not to "save" money.Coverage in the absence of quantification of effectiveness. Many aspects of health care that are common practice have not been tested; many are not testable.
Most of these are not "high ticket items." However, some provision needsto be made for their indemnification. For example, it is proposed that each insured
worker will be afforded a certain number of primary-care hours each year(one or two) and counseling hours (one or two) without co-pay under Plan B. Hours not expended will accumulate. Additional hours incur 100 percent copay,
which can be funded through Plan A. Administering the PlanThe entire indem nity scheme will be online. Each provider will have a PIN to access a personal web page, and each insured worker will have a PIN. The provider
224 I ASSURIN(i HEALTH, INSURIN(i DISEASEweb interface will be interactive. Based on details of the diagnosis, available options will be listed with co-pay. That is true even if a patient is a candidate for hospitalization or arrives at an emergency department. For pharmaceuticals, the worker will be offered a menu of pharmacies convenient to his/her residence
when enrolling. Prescriptions will also be accessed online.Billing will be electronic at the point of service and at the time of service. Moneys will be transferred instantly to the provider's bank account. Administrative
overhead will be minimized for providers and the plan.Every insured worker will receive a summary of the charges. If the worker has ready access to the Internet, an e-mail will instruct the worker to visit a personal website. Otherwise, summaries will be mailed. The worker will be responsible for monitoring the accuracy of charges. Software exists for nearly all the elements of this process, albeit for other purposes in the current healthcare
delivery system. Cost/EffectivenessBased on the per capita health-care expenditures in other resource- advantaged countries, it is likely that no more than 5 percent of wages is required to insure a worker and family under Plan B. This reflects the value inherent in underwriting only effective interventions and the savings inherent in an online processing scheme. It is hoped that pressure can be brought to bear on the U.S. proVider enterprise to reduce the current 50 percent overhead costs by more than 50 percent, bringing them into the range of the national health schemes operating elsewhere. That would lead to a substantial increment in moneys funding Plan A by further reducing the cost of the effective "health benefits" under Plan B.
"Quality"The indemnity scheme is designed to be intrinsically free of moral hazard by institutionalizing the fiduciary responsibility of its administration. The design also facilitates minimizing moral hazard on the part of providers and patients. Effective care is its raison d' etre. Measuring "quality" in terms of efficiency and safety is rational in a scheme that indemnifies effectiveness. It is also highly feasible in a scheme that utilizes the Internet so extensively. Even pharmacovigilance
becomes feasible; patients can be monitored for the incidence of adverse drug effects over time. ASSURING HEALTH, INSURING DISEASE I 225
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Health-care Robert Tapp, September 7 2009
- Re: Health-care Carol Koepp, September 7 2009
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